Dr Hua Cui


Professor & Head

Analytical Chemistry Division

Department of Chemistry

University of Science and Technology of China

No. 96 Jinzhai Road, Hefei, Anhui 230026, China

Phone: 00-86-551-63600730

Fax: 00-86-551-63600730

Email: hcui@ustc.edu.cn

ORCID: orcid.org/0000-0003-4769-9464


Hua Cui is currently Professor of Analytical Chemistry at University of Science and Technology of China, China. She received her Ph.D. from University of Science and Technology of China in 1990. She was appointed as a lecturer in 1990, as an associate professor in 1995 and as a professor & head in 2000 in Analytical Division, Department of Chemistry, University of Science and Technology of China. During the time, she also conducted some research work as a postdoctoral at Department of Pharmaceutical Analysis, Faculty of Pharmacy, Utrecht University and as a visiting scholars at Department of Biology, Jackson State University. She received Award for The National Science Fund for Distinguished Young Scholars from The National Natural Science Foundation of China in 2006, Liang Shuquan Award for Basic Research in Analytical Chemistry from Chinese Chemical Society in 2012, Award for 4nd Ten Outstanding Women Award from The Chinese Academy of Science in 2013 and Outstanding Women Analytical Chemist Award from Analytical Chemistry Division of Chinese Chemical Society in 2015. In 2014, she was appointed as a Member of the Council of the International Society of Bioluminescence and Chemiluminescence. In 2016, she was appointed as an Editor of Analytical and Bioanalytical Chemistry. She has also been serving as a member of editoral advisory board of ACS Sensor and Chinese J. of Analytical Chemistry.


Her research interests are analytical chemiluminescence (CL) and electrochemiluminescence (ECL), and their applications in interdisciplinary fields including public health, food safety, and environmental monitoring. Over the past 32 years, great progress has been made by her research group to develop new CL/ECL-based analytical concept and principle and to better understand these analytical methods. Her group has developed a potential-resolved ECL method that has become an effective tool for studying ECL mechanisms. Her group has pioneered the study of metal nanoparticle-initiated CL and ECL, and developed direct strategies for the preparation of a variety of CL/ECL functionalized nanomaterials and ultrasensitive CL/ECL biosensors. Very recently, ground breaking progress has been made in CL reagent/catalyst bifunctionalized nanomaterials, which enabled unique and superior catalytic activity for the catalysts grafted on the surface of CL/ECL functional nanomaterials. These results have provided novel strategies to address fundamental challenges of CL and ECL as powerful analytical and bioanalytical methods. Moreover, she has authored and co-authored over 130 publications on reputed international journals; She has been invited to deliver plenary lectures at international conferences such as International Symposium on Bioluminescence & Chemiluminescence and workshop on Electrogenerated Chemiluminescence, etc.



1.     Y.T Liu, W. S, Q. Li, J.N Shu, L.F. Gao, M.M Ma, W. Wang and H Cui* "Firefly-mimicking intensive and long-lasting chemiluminescence hydrogels". Nature Commun., 2017, 8:1003, DOI: 10.1038/s41467-017-01101-6.

2.     W.J Kong, X.N Zhao, Q.J Zhu, L.F Gao, and H. Cui*. "Highly Chemiluminescent Magnetic Beads for Label-Free Sensing of 2,4,6-Trinitrotoluene". Anal. chem., 2017, 89 (13), pp 7145–7151.

3.     Z.L. Han, F. Li, J.N. Shu, L.F. Gao, X.Y. Liu, and H. Cui*, "Acridinium Ester-Functionalized Carbon Nanomaterials: General Synthesis Strategy and Outstanding Chemiluminescence", ACS Appl. Mater. Inter., 2016, 7 (27), 17454-17460.

4.     Q. Li, F. Li, W. Shen, X.Y. Liu, and H. Cui*, "Lucigenin/Co(tryptophan)2 complex bifunctionalized graphene oxide: facile synthesis and unique chemiluminescence", J. Mater. Chem. C., 2016, 4, 3477-3484.

5.     G.X. Li, X.X. Yu, D.Q. Liu, X.Y. Liu, F. Li, and H. Cui*, "Label-Free Electro chemiluminescence Aptasensor for 2,4,6-Trinitrotoluene Based on Bilayer Structure of Luminescence Functionalized Graphene Hybrids", Anal. chem., 2015, 87, 10976-10981.

6.     G.X. Li, X.X. Yu, D.Q. Liu, X.Y. Liu, F. Li, and H. Cui*, "Label-Free Electro chemiluminescence Aptasensor for 2,4,6-Trinitrotoluene Based on Bilayer Structure of Luminescence Functionalized Graphene Hybrids", Anal. chem., 2015, 87, 10976-10981.

7.     J.N. Shu, W. Wang, and H. Cui*, "Direct electrochemiluminescence of gold nanoparticles bifunctionalized by luminol analogue–metal complexes in neutral and alkaline media", Chem. Commun., 2015, 51, 11366–11369 (back cover).

8.     H.L. Zhang, Z.L. Han, X. Wang, F. Li, H. Cui*, D. Yang, and Z.P. Bian, "Sensitive Immunosensor for N-Terminal Pro-brain Natriuretic Peptide Based on N-(Aminobutyl)-N-(ethylisoluminol)-Functionalized Gold Nanodots/Multiwalled Carbon Nanotube Electrochemiluminescence Nanointerface", ACS Appl. Mater. Inter., 2015, 7 (14), 7599-7604.

9.     X.Y. Liu , Z.L. Han , F. Li , L.F. Gao , G.L. Liang , and H. Cui*, "Highly Chemiluminescent Graphene Oxide Hybrids Bifunctionalized by N-(aminobutyl)-N-(ethylisoluminol)/ Horseradish Peroxidase and Sensitive Sensing of Hydrogen Peroxide", ACS Appl. Mater. Inter., 2015, 7 (33), 18283-18291.

10. S.Y. Li , D.Y. Chen , Q.T. Zhou , W. Wang , L.F. Gao , J. Jiang , H.J. Liang , Y.Z. Liu , G.L. Liang , and H. Cui*, "A General Chemiluminescence Strategy for Measuring Aptamer–Target Binding and Target Concentration", Anal. Chem., 2014, 86 (11), 5559–5566.

11. M.X. Liu, H.L. Zhang, J.N. Shu, X.Y Liu, F. Li, and H. Cui*, "Gold Nanoparticles Bifunctionalized by Chemiluminescence Reagent and Catalyst Metal Complexes: Synthesis and Unique Chemiluminescence Property", Anal. Chem., 2014, 86 (6), 2857–2861.

12. F. Li, Y.Q. Yu, Q. Li, M. Zhou, H. Cui*, "A Homogeneous Signal-On Strategy for the Detection of rpoB Genes of Mycobacterium tuberculosis Based on Electrochemiluminescent Graphene Oxide and Ferrocene Quenching", Anal. Chem., 2014, 86 (3), 1608-1613.

13. Y. He , X. He , X.Y. Liu , L.F. Gao , and H. Cui*, "Dynamically tunable chemiluminescence of luminol functionalized silver nanoparticles and its application to protein sensing arrays", Anal. Chem., 2014. 86 (24), 12166 - 12171.

14. H.L. Zhang and H. Cui*, "High-density assembly of chemiluminescence functionalized gold nanodots on multiwalled carbon nanotubes and their application as biosensing platforms", Nanoscale, 2014, 6(5), 2563 - 2566.

15. L.F. Gao, H.L. Zhang, H. Cui*, "A general strategy to prepare homogeneous and reagentless GO/lucigenin&enzyme biosensors for detection of small biomolecules", Biosens. Bioelectron., 2014, 57, 65-70.

16. Y. He, Y.T. Chen, C.Y. Li and H. Cui*"Molecular Encoder - Decoder Based on Assembly of Graphene with Dye-labeled DNA", Chem. Commun., 2014, 50, 7994-7997.

17. F. Li, Y.T. Liu, M. Zhuang, H.L. Zhang, H. Cui*, "Biothiols as chelators for preparation of N-(aminobutyl)-N-(ethylisoluminol)/Cu2+ complexes bifunctionalized gold nanoparticles and sensitive sensing of pyrophosphate ion", ACS Appl. Mater. Inter., 2014, 6, 18104-18111.

18. N. Li, D.Q. Liu, H. Cui*, "Metal-nanoparticle-involved chemiluminescence and its applications in bioassays", Anal. Bioanal. Chem., 2014, 406(23), 5561-5571.

19. Y. He, G.M. Huang, and H. Cui*, "Quenching the Chemiluminescence of Acridinium Ester by Graphene Oxide for Label-Free and Homogeneous DNA Detection", ACS Appl. Mater. Interfaces, 2013, 5 (21), 11336–11340.

20. Y. He, H. Cui*, "Chemiluminescent Logic Gates Based on Functionalized Gold Nanoparticles/Graphene Oxide Nanocomposites", Chemistry - A European Journal, 2013, 19(40), 13584–13589.

21. F. Li, H. Cui*, "A label-free electrochemiluminescence aptasensor for thrombin based on novel assembly strategy of oligonucleotide and luminol functionalized gold nanoparticles", Biosens. Bioelectron., 2013, 39, 261-267.

22. Y.Q. Yu, Q. Cao, M. Zhou, H. Cui*, "A novel homogeneous label-free aptasensor for 2,4,6-trinitrotoluene detection based on an assembly strategy of electrochemiluminescent graphene oxide with gold nanoparticles and aptamer", Biosens. Bioelectron., 2013, 43. 137–142.

23. Y. He, H. Cui*, "Label free and homogeneous histone sensing based on chemiluminescence resonance energy transfer between lucigenin and gold nanoparticles", Biosens. Bioelectron., 2013, (47), 313-317

24.  Y. He, G.M. Huang, J. Jiang, Q. Zhang, H. Cui*, "Preparation and electrochemiluminescent and photoluminescent properties of a graphene oxide colloid", Carbon., 2013, (56), 201-207.

25. D.Q. Liu, G.M. Huang, Y.Q. Yu, Y. He, H.L. Zhang and H. Cui*, "N-(Aminobutyl)-N-(ethylisoluminol) and hemin dual-functionalized graphene hybrids with high chemiluminescence", Chem. Commun., 2013, 49, 9794-9796.

26. Y. He, H. Cui**, “Synthesis of Dendritic Platinum Nanoparticles/Lucigenin/Reduced Graphene Oxide Hybrid with Chemiluminescence Activity”, Chem. Eur. J., 2012, 18, 4823-4826.

27. Y. He, H. Cui*, “Synthesis of highly chemiluminescent graphene oxide/silver nanoparticle nano-composites and their analytical applications”, J. Mater. Chem., 2012, 22, 9086-9091.

28. W. Shen, Y.Q. Yu, J.N. Shu, H. Cui*, “A graphene-based composite material noncovalently functionalized with a chemiluminescence reagent: synthesis and intrinsic chemiluminescence activity”, Chem. Commun., 2012, 48, 2894-2896.

29. Y. He, H. Cui*, “Fabrication of Luminol and Lucigenin Bifunctionalized Gold Nnanoparticles/Graphene Oxide Nanocomposites with Dual-Wavelength Chemiluminescence”, J. Phys. Chem. C, 2012, 116, 12593-12597.

30. Y.Q. Yu, M. Zhou, W. Shen, H.L. Zhang, Q. Cao, H. Cui*, “Synthesis of electrochemiluminescent graphene oxide functionalized with a ruthenium(II) complex and its use in the detection of tripropylamine, Carbon, 2012, 50, 2539-2545.

31. W. Shen, D.Y. Tian, H. Cui*, D. Yang, Z.P. Bian, “Nanoparticle-based electrochemiluminescence immunosensor with enhanced sensitivity for cardiac troponin I using N-(aminobutyl)-N-(ethylisoluminol)-functionalized gold nanoparticles as labels”, Biosens. Bioelectron., 2011, 27, 18-24.

32. D.Y. Tian, Y. Chai, H.L. Zhang, H. Cui*, “Synthesis of N-(aminobutyl)-N-(ethylisoluminol) functionalized gold nanomaterials for chemiluminescent bio-probe”, Chem. Commun., 2011, 47, 4959-4961.

33. Y. He, D.Q. Liu, X.Y. He, H. Cui*, “One-pot synthesis of luminol functionalized silver nanoparticles with chemiluminescence activity for ultrasensitive DNA sensing”, Chem. Commun., 2011, 47, 10692-10694.

34. Y.Q. Yu, M. Zhou, H. Cui*, “Synthesis and electrochemiluminescence of bis(2,2'- bipyridine)(5-amino-1,10-phenanthroline) ruthenium(II)-functionalized gold nanoparticles”, J. Mater. Chem., 2011, 21, 12622-12625.

35. D.Y. Tian, C.F. Duan, W. Wang, H. Cui*, "Ultrasensitive electrochemiluminescence immunosensor based on luminol functionalized gold nanoparticle labeling", Biosens. Bioelectron., 2010, 25, 2290-2295. 

36. N. Li, W. Wang, D.Y. Tian, H. Cui*, “pH-dependent catalytic properties of Pd–Ag nanoparticles in luminol chemiluminescence”, Chem. Commun., 2010, 46, 1520-1522.

37. Y. Chai, D.Y. Tian, W. Wang, H. Cui*, “A novel electrochemiluminescence strategy for ultrasensitive DNA assay using luminol functionalized gold nanoparticles multi-labeling and amplification of gold nanoparticles and biotin-streptavidin system”, Chem. Commun., 2010, 46, 7560-7562.

38. C.F. Duan, H. Cui*, “Time-tunable autocatalytic lucigenin chemiluminescence initiated by platinum nanoparticles and ethanol”, Chem. Commun., 2009, 18, 2574-2576.

39. H. Zhang, H. Cui*, "Synthesis and Characterization of Functionalized Ionic Liquid-Stabilized Metal (Gold and Platinum) Nanoparticles and Metal Nanoparticle/Carbon Nanotube Hybrids", Langmuir, 2009, 25, 2604-2612.

40. H. Cui*, J.Z. Guo, N. Li, L.J. Liu, "Gold nanoparticle triggered chemilumineseence between luminol and AgNO3", J. Phys. Chem. C, 2008, 112, 11319-11323.

41. W. Wang, T. Xiong, H. Cui*, "Fluorescence and electrochemiluminescence of luminol-reduced gold nanoparticles: Photostability and platform effect", Langmuir, 2008, 24(6):2826-2833.

42. W. Wang, X. Yang, H. Cui*, "Growth mechanism of flowerlike gold nanostructures: surface plasmon resonance (SPR) and resonance rayleigh scattering (RRS) approaches to growth monitoring", J. Phys. Chem. C, 2008, 112, 16348-16353.

43. Y.P. Dong, H. Cui*, Y. Xu, "Comparative studies on electrogenerated chemiluminescence of luminol on gold nanoparticle modified electrodes", Langmuir, 2007, 23(2), 523-529.

44. H. Cui*, W. Wang, C.F. Duan, Y.P. Dong, J.Z. Guo, "Synthesis, characterization, and electrochemiluminescence of luminol-reduced gold nanoparticles and their application in a hydrogen peroxide sensor", Chem. Eur. J., 2007, 13 (24): 6975-6984.

45. Z.F. Zhang, H. Cui*, M.J. Shi, "Chemiluminescence accompanied by the reaction of gold nanoparticles with potassium permanganate", Phys. Chem. Chem. Phys., 2006, 8(8), 1017-1021.

46. H. Cui*, Z.F. Zhang, M.J. Shi, Y. Xu, Y.L. Wu, "Light Emission of Gold Nanoparticles Induced by the Reaction of Bis(2,4,6-trichlorophenyl) Oxalate and Hydrogen Peroxide", Anal. Chem., 2005, 77(19), 6402-6406.

47. H. Cui*, Z.F. Zhang, M.J. Shi, “Chemiluminescent Reactions Induced by Gold Nanoparticles”, J. Phys. Chem. B, 2005, 109, 3099-3103.

48. Z.F. Zhang, H. Cui*, C.Z. Lai, L.J. Liu, “Gold nanoparticles-catalyzed luminol chemiluminescence and its analytical applications”, Anal. Chem., 2005, 77(10), 3324-3329.

49. Q.L. Zhang, H. Cui*, A. Myint, M. Lian, L.J. Liu, "Sensitive determination of phenolic compounds using high-performance liquid chromatography with cerium(IV)-rhodamine 6G-phenolic compound chemiluminescence detection", J. Chromatogr. A, 2005, 1095(1-2), 94-101.

50. H. Xu, C.F. Duan, Z.F. Zhang, J.Y. Chen, C.Z. Lai, M. Lian, L.J. Liu, H. Cui*, “Flow injection determination of p-aminophenol at trace level using inhibited luminol-dimethylsulfoxide-NaOH-EDTA chemiluminescence”, Water Res., 2005, 39(23), 396-402.

51. H. Cui*, Y. Xu, Z.F. Zhang, “Multi-channel electrochemiluminescence of luminol in neutral and alkaline aqueous solutions on a gold nanoparticles self-assembled electrode” Anal. Chem., 2004, 76, 13, 4002-4010.

52. H. Cui*, Y. Xu, Z.F. Zhang, “Multi-channel electrochemiluminescence of luminol in neutral and alkaline aqueous solutions on a gold nanoparticles self-assembled electrode” Anal. Chem., 2004, 76, 13, 4002-4010.

53. H. Cui*, G.Z. Zou, X.Q. Lin, “Electrochemiluminescence of luminol in alkaline solution at a paraffin-impregnated graphite electrode”, Anal. Chem., 2003, 75, 324-331.

54. C.G. Xie, H. Cui*, “Detection of tannic acid at trace level in industrial wastewaters using a highly sensitive chemiluminescence method” Water Res., 2003, 37, 233-237.

55. H. Cui, H.M. Hwang*, K, Zeng, H. Glover, H.T. Yu, Y.M. Liu, “Riboflavin-photosensitized degradation of atrazine in a freshwater environment” Chemosphere, 2002, 47, 991-999.

56. H. Cui*, C.X. He, and G.W. Zhao, “Determination of polyphenols by high-performance liquid chromatography with inhibited chemiluminescence detection”, J. Chromatogr. A, 1999, 855(1), 171-179.

57. H. Cui, L.E. Reusaet and A. Bult*, “The precolumn fluorescent derivatization of antagonist [Arg6, D-Trp7,9, MePhe8]- substance P {6-11} with benzoin in HPLC and selective determination of arginine - containing fragments in its degradation products”, J. Chromatogr. A, 1996, 736, 91-96.

58. H. Cui, L.E. Reusaet and A. Bult*, “Selective determination of peptides containing specific amino acid residues in high performance liquid chromatography and capillary electrophoresis”, J. Chromatogr. A, 1995, 704, 27-36.