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Hua Cui
is currently Professor of Analytical Chemistry at University of Science and
Technology of China, China. She received her Ph.D. from University of Science
and Technology of China in 1990. She was appointed as a lecturer in 1990,
as an associate professor in 1995 and as a professor & head in 2000 in
Analytical Division, Department of Chemistry, University of Science and
Technology of China. During the time, she also conducted some research work
as a postdoctoral at Department of Pharmaceutical Analysis, Faculty of
Pharmacy, Utrecht University and as a visiting scholars
at Department of Biology, Jackson State University. She received Award for
The National Science Fund for Distinguished Young Scholars from The
National Natural Science Foundation of China in 2006, Liang Shuquan Award for Basic Research in Analytical
Chemistry from Chinese Chemical Society in 2012, Award for 4nd Ten
Outstanding Women Award from The Chinese Academy of Science in 2013 and
Outstanding Women Analytical Chemist Award from Analytical Chemistry
Division of Chinese Chemical Society in 2015. In 2014, she was appointed as
a Member of the Council of the International Society of Bioluminescence and
Chemiluminescence. In 2016, she was appointed as
an Editor of Analytical and Bioanalytical Chemistry. She has also been
serving as a member of editoral advisory board of
ACS Sensor and Chinese J. of Analytical Chemistry.
RESEARCH INTERESTS
Her
research interests are analytical chemiluminescence
(CL) and electrochemiluminescence (ECL), and
their applications in interdisciplinary fields including public health,
food safety, and environmental monitoring. Over the past 32 years, great
progress has been made by her research group to develop new CL/ECL-based
analytical concept and principle and to better understand these analytical
methods. Her group has developed a potential-resolved ECL method that has
become an effective tool for studying ECL mechanisms. Her group has
pioneered the study of metal nanoparticle-initiated CL and ECL, and
developed direct strategies for the preparation of a variety of CL/ECL
functionalized nanomaterials and ultrasensitive CL/ECL biosensors. Very
recently, ground breaking progress has been made in CL reagent/catalyst bifunctionalized nanomaterials, which enabled unique
and superior catalytic activity for the catalysts grafted on the surface of
CL/ECL functional nanomaterials. These results have provided novel
strategies to address fundamental challenges of CL and ECL as powerful
analytical and bioanalytical methods. Moreover, she has authored and
co-authored over 130 publications on reputed international journals; She
has been invited to deliver plenary lectures at international conferences
such as International Symposium on Bioluminescence & Chemiluminescence and workshop on Electrogenerated
Chemiluminescence, etc.
REPRESENTATIVE PUBLICATIONS
1. Y.T
Liu, W. S, Q. Li, J.N Shu, L.F. Gao, M.M Ma, W. Wang and H Cui* "Firefly-mimicking
intensive and long-lasting chemiluminescence
hydrogels". Nature Commun., 2017, 8:1003, DOI:
10.1038/s41467-017-01101-6.
2.
W.J Kong, X.N Zhao, Q.J Zhu, L.F
Gao, and H. Cui*. "Highly
Chemiluminescent Magnetic Beads for Label-Free Sensing of
2,4,6-Trinitrotoluene". Anal. chem., 2017, 89 (13), pp
7145–7151.
3. Z.L.
Han, F. Li, J.N. Shu, L.F. Gao, X.Y. Liu, and H. Cui*, "Acridinium
Ester-Functionalized Carbon Nanomaterials: General Synthesis Strategy and
Outstanding Chemiluminescence", ACS Appl.
Mater. Inter., 2016, 7 (27), 17454-17460.
4. Q.
Li, F. Li, W. Shen, X.Y. Liu, and H.
Cui*, "Lucigenin/Co(tryptophan)2 complex bifunctionalized graphene oxide: facile synthesis and
unique chemiluminescence", J. Mater. Chem.
C., 2016, 4, 3477-3484.
5. G.X.
Li, X.X. Yu, D.Q. Liu, X.Y. Liu, F. Li, and H. Cui*, "Label-Free Electro chemiluminescence
Aptasensor for 2,4,6-Trinitrotoluene Based on
Bilayer Structure of Luminescence Functionalized Graphene Hybrids", Anal. chem., 2015, 87, 10976-10981.
6. G.X.
Li, X.X. Yu, D.Q. Liu, X.Y. Liu, F. Li, and H. Cui*, "Label-Free Electro chemiluminescence
Aptasensor for 2,4,6-Trinitrotoluene Based on
Bilayer Structure of Luminescence Functionalized Graphene Hybrids", Anal. chem., 2015, 87, 10976-10981.
7. J.N.
Shu, W. Wang, and H. Cui*,
"Direct electrochemiluminescence of gold
nanoparticles bifunctionalized by luminol analogue–metal complexes in neutral and
alkaline media", Chem. Commun., 2015, 51, 11366–11369 (back cover).
8. H.L.
Zhang, Z.L. Han, X. Wang, F. Li, H.
Cui*, D. Yang, and Z.P. Bian, "Sensitive
Immunosensor for N-Terminal Pro-brain Natriuretic Peptide Based on N-(Aminobutyl)-N-(ethylisoluminol)-Functionalized
Gold Nanodots/Multiwalled
Carbon Nanotube Electrochemiluminescence Nanointerface", ACS Appl. Mater. Inter., 2015, 7 (14), 7599-7604.
9. X.Y.
Liu , Z.L. Han , F. Li , L.F. Gao , G.L. Liang ,
and H. Cui*, "Highly
Chemiluminescent Graphene Oxide Hybrids Bifunctionalized
by N-(aminobutyl)-N-(ethylisoluminol)/
Horseradish Peroxidase and Sensitive Sensing of Hydrogen Peroxide", ACS Appl. Mater. Inter., 2015, 7
(33), 18283-18291.
10. S.Y.
Li , D.Y. Chen , Q.T. Zhou , W. Wang , L.F. Gao ,
J. Jiang , H.J. Liang , Y.Z. Liu , G.L. Liang , and H. Cui*, "A General Chemiluminescence
Strategy for Measuring Aptamer–Target Binding and Target
Concentration", Anal. Chem., 2014, 86 (11), 5559–5566.
11. M.X.
Liu, H.L. Zhang, J.N. Shu, X.Y Liu, F. Li, and H. Cui*, "Gold Nanoparticles Bifunctionalized
by Chemiluminescence Reagent and Catalyst Metal
Complexes: Synthesis and Unique Chemiluminescence
Property", Anal. Chem.,
2014, 86 (6), 2857–2861.
12. F.
Li, Y.Q. Yu, Q. Li, M. Zhou, H. Cui*,
"A Homogeneous Signal-On Strategy for the Detection of rpoB Genes of Mycobacterium tuberculosis
Based on Electrochemiluminescent Graphene Oxide
and Ferrocene Quenching", Anal. Chem., 2014, 86 (3), 1608-1613.
13. Y.
He , X. He , X.Y. Liu ,
L.F. Gao , and H. Cui*,
"Dynamically tunable chemiluminescence of luminol functionalized silver nanoparticles and its
application to protein sensing arrays", Anal. Chem., 2014. 86 (24), 12166 - 12171.
14. H.L.
Zhang and H. Cui*,
"High-density assembly of chemiluminescence
functionalized gold nanodots on multiwalled carbon nanotubes and their application as biosensing platforms", Nanoscale, 2014, 6(5), 2563 - 2566.
15. L.F.
Gao, H.L. Zhang, H. Cui*,
"A general strategy to prepare homogeneous and reagentless
GO/lucigenin&enzyme biosensors for detection
of small biomolecules", Biosens. Bioelectron.,
2014, 57, 65-70.
16. Y.
He, Y.T. Chen, C.Y. Li and H. Cui*，"Molecular
Encoder - Decoder Based on Assembly of Graphene with Dye-labeled DNA",
Chem. Commun., 2014, 50, 7994-7997.
17. F.
Li, Y.T. Liu, M. Zhuang, H.L. Zhang, H.
Cui*, "Biothiols as chelators for
preparation of N-(aminobutyl)-N-(ethylisoluminol)/Cu2+ complexes bifunctionalized gold nanoparticles and sensitive
sensing of pyrophosphate ion", ACS
Appl. Mater. Inter., 2014, 6, 18104-18111.
18. N.
Li, D.Q. Liu, H. Cui*,
"Metal-nanoparticle-involved chemiluminescence
and its applications in bioassays", Anal. Bioanal. Chem., 2014, 406(23), 5561-5571.
19. Y.
He, G.M. Huang, and H. Cui*,
"Quenching the Chemiluminescence of Acridinium Ester by Graphene Oxide for Label-Free and
Homogeneous DNA Detection", ACS Appl. Mater. Interfaces, 2013, 5 (21),
11336–11340.
20. Y.
He, H. Cui*,
"Chemiluminescent Logic Gates Based on Functionalized Gold
Nanoparticles/Graphene Oxide Nanocomposites", Chemistry - A
European Journal, 2013,
19(40), 13584–13589.
21. F.
Li, H. Cui*, "A label-free electrochemiluminescence aptasensor
for thrombin based on novel assembly strategy of oligonucleotide and luminol functionalized gold nanoparticles", Biosens. Bioelectron., 2013, 39, 261-267.
22. Y.Q.
Yu, Q. Cao, M. Zhou, H. Cui*,
"A novel homogeneous label-free aptasensor
for 2,4,6-trinitrotoluene detection based on an assembly strategy of electrochemiluminescent graphene oxide with gold
nanoparticles and aptamer", Biosens.
Bioelectron., 2013, 43. 137–142.
23. Y.
He, H. Cui*, "Label free
and homogeneous histone sensing based on chemiluminescence
resonance energy transfer between lucigenin and gold nanoparticles", Biosens. Bioelectron., 2013, (47), 313-317
24. Y. He, G.M. Huang, J. Jiang, Q.
Zhang, H. Cui*,
"Preparation and electrochemiluminescent and
photoluminescent properties of a graphene oxide
colloid", Carbon., 2013,
(56), 201-207.
25. D.Q.
Liu, G.M. Huang, Y.Q. Yu, Y. He, H.L. Zhang and H. Cui*, "N-(Aminobutyl)-N-(ethylisoluminol)
and hemin dual-functionalized graphene hybrids with high chemiluminescence", Chem. Commun.,
2013, 49, 9794-9796.
26. Y.
He, H. Cui**, “Synthesis of
Dendritic Platinum Nanoparticles/Lucigenin/Reduced Graphene Oxide Hybrid
with Chemiluminescence Activity”, Chem. Eur. J., 2012, 18, 4823-4826.
27. Y.
He, H. Cui*, “Synthesis of
highly chemiluminescent graphene oxide/silver nanoparticle nano-composites and their analytical applications”, J. Mater. Chem., 2012, 22,
9086-9091.
28. W.
Shen, Y.Q. Yu, J.N. Shu, H. Cui*, “A graphene-based composite
material noncovalently functionalized with a chemiluminescence reagent: synthesis and intrinsic chemiluminescence activity”, Chem. Commun., 2012, 48, 2894-2896.
29. Y.
He, H. Cui*, “Fabrication of Luminol and Lucigenin Bifunctionalized
Gold Nnanoparticles/Graphene Oxide Nanocomposites
with Dual-Wavelength Chemiluminescence”, J. Phys. Chem. C, 2012, 116,
12593-12597.
30. Y.Q.
Yu, M. Zhou, W. Shen, H.L. Zhang, Q. Cao, H. Cui*, “Synthesis of electrochemiluminescent
graphene oxide functionalized with a ruthenium(II) complex and its use in
the detection of tripropylamine”, Carbon, 2012, 50, 2539-2545.
31. W.
Shen, D.Y. Tian, H. Cui*, D.
Yang, Z.P. Bian, “Nanoparticle-based electrochemiluminescence immunosensor
with enhanced sensitivity for cardiac troponin I using N-(aminobutyl)-N-(ethylisoluminol)-functionalized
gold nanoparticles as labels”, Biosens. Bioelectron.,
2011, 27, 18-24.
32. D.Y.
Tian, Y. Chai, H.L. Zhang, H. Cui*,
“Synthesis of N-(aminobutyl)-N-(ethylisoluminol) functionalized gold nanomaterials for
chemiluminescent bio-probe”, Chem. Commun., 2011, 47, 4959-4961.
33. Y.
He, D.Q. Liu, X.Y. He, H. Cui*,
“One-pot synthesis of luminol functionalized
silver nanoparticles with chemiluminescence
activity for ultrasensitive DNA sensing”, Chem. Commun., 2011, 47, 10692-10694.
34. Y.Q.
Yu, M. Zhou, H. Cui*, “Synthesis
and electrochemiluminescence of bis(2,2'-
bipyridine)(5-amino-1,10-phenanthroline)
ruthenium(II)-functionalized gold nanoparticles”, J. Mater. Chem., 2011, 21, 12622-12625.
35. D.Y.
Tian, C.F. Duan, W. Wang, H. Cui*, "Ultrasensitive electrochemiluminescence
immunosensor based on luminol
functionalized gold nanoparticle labeling", Biosens. Bioelectron., 2010, 25,
2290-2295.
36. N.
Li, W. Wang, D.Y. Tian, H. Cui*,
“pH-dependent catalytic properties of Pd–Ag
nanoparticles in luminol chemiluminescence”,
Chem. Commun.,
2010, 46, 1520-1522.
37. Y.
Chai, D.Y. Tian, W. Wang, H. Cui*,
“A novel electrochemiluminescence strategy for
ultrasensitive DNA assay using luminol
functionalized gold nanoparticles multi-labeling and amplification of gold
nanoparticles and biotin-streptavidin system”, Chem. Commun., 2010, 46, 7560-7562.
38. C.F.
Duan, H.
Cui*, “Time-tunable autocatalytic lucigenin chemiluminescence
initiated by platinum nanoparticles and ethanol”, Chem. Commun., 2009, 18, 2574-2576.
39. H.
Zhang, H. Cui*, "Synthesis
and Characterization of Functionalized Ionic Liquid-Stabilized Metal (Gold
and Platinum) Nanoparticles and Metal Nanoparticle/Carbon Nanotube
Hybrids", Langmuir, 2009,
25, 2604-2612.
40. H. Cui*,
J.Z. Guo, N. Li, L.J. Liu, "Gold
nanoparticle triggered chemilumineseence between luminol and AgNO3", J. Phys. Chem. C, 2008, 112,
11319-11323.
41. W.
Wang, T. Xiong, H. Cui*, "Fluorescence and electrochemiluminescence
of luminol-reduced gold nanoparticles: Photostability and platform effect", Langmuir, 2008, 24(6):2826-2833.
42. W.
Wang, X. Yang, H. Cui*,
"Growth mechanism of flowerlike gold nanostructures: surface plasmon resonance (SPR) and resonance rayleigh scattering (RRS) approaches to growth
monitoring", J. Phys. Chem. C,
2008, 112, 16348-16353.
43. Y.P.
Dong, H. Cui*, Y. Xu,
"Comparative studies on electrogenerated chemiluminescence of luminol
on gold nanoparticle modified electrodes", Langmuir, 2007, 23(2), 523-529.
44. H. Cui*,
W. Wang, C.F. Duan, Y.P. Dong, J.Z. Guo, "Synthesis, characterization, and electrochemiluminescence of luminol-reduced
gold nanoparticles and their application in a hydrogen peroxide sensor",
Chem. Eur. J., 2007, 13 (24):
6975-6984.
45. Z.F.
Zhang, H. Cui*, M.J. Shi, "Chemiluminescence accompanied by the reaction of gold
nanoparticles with potassium permanganate", Phys. Chem. Chem. Phys., 2006, 8(8), 1017-1021.
46. H. Cui*,
Z.F. Zhang, M.J. Shi, Y. Xu, Y.L. Wu, "Light Emission of Gold
Nanoparticles Induced by the Reaction of Bis(2,4,6-trichlorophenyl)
Oxalate and Hydrogen Peroxide", Anal.
Chem., 2005, 77(19), 6402-6406.
47. H. Cui*,
Z.F. Zhang, M.J. Shi, “Chemiluminescent Reactions Induced by Gold
Nanoparticles”, J. Phys. Chem. B,
2005, 109, 3099-3103.
48. Z.F.
Zhang, H. Cui*, C.Z. Lai, L.J.
Liu, “Gold nanoparticles-catalyzed luminol chemiluminescence and its analytical applications”, Anal. Chem., 2005, 77(10),
3324-3329.
49. Q.L.
Zhang, H. Cui*, A. Myint, M. Lian, L.J. Liu,
"Sensitive determination of phenolic compounds using high-performance
liquid chromatography with cerium(IV)-rhodamine 6G-phenolic compound chemiluminescence detection", J. Chromatogr. A, 2005, 1095(1-2),
94-101.
50. H.
Xu, C.F. Duan, Z.F. Zhang, J.Y. Chen, C.Z. Lai,
M. Lian, L.J. Liu, H. Cui*, “Flow injection determination of p-aminophenol at
trace level using inhibited luminol-dimethylsulfoxide-NaOH-EDTA chemiluminescence”, Water Res., 2005, 39(23), 396-402.
51. H. Cui*,
Y. Xu, Z.F. Zhang, “Multi-channel electrochemiluminescence
of luminol in neutral and alkaline aqueous
solutions on a gold nanoparticles self-assembled electrode” Anal. Chem., 2004, 76, 13,
4002-4010.
52. H. Cui*,
Y. Xu, Z.F. Zhang, “Multi-channel electrochemiluminescence
of luminol in neutral and alkaline aqueous
solutions on a gold nanoparticles self-assembled electrode” Anal. Chem., 2004, 76, 13,
4002-4010.
53. H. Cui*,
G.Z. Zou, X.Q. Lin, “Electrochemiluminescence of luminol in alkaline solution at a paraffin-impregnated
graphite electrode”, Anal. Chem.,
2003, 75, 324-331.
54. C.G.
Xie, H.
Cui*, “Detection of tannic acid at trace level in industrial
wastewaters using a highly sensitive chemiluminescence
method” Water Res., 2003, 37,
233-237.
55. H. Cui,
H.M. Hwang*, K, Zeng, H. Glover, H.T. Yu, Y.M. Liu,
“Riboflavin-photosensitized degradation of atrazine in a freshwater
environment” Chemosphere, 2002,
47, 991-999.
56. H. Cui*,
C.X. He, and G.W. Zhao, “Determination of polyphenols by high-performance
liquid chromatography with inhibited chemiluminescence
detection”, J. Chromatogr. A, 1999, 855(1), 171-179.
57. H. Cui,
L.E. Reusaet and A. Bult*,
“The precolumn fluorescent derivatization of
antagonist [Arg6, D-Trp7,9, MePhe8]-
substance P {6-11} with benzoin in HPLC and selective determination of
arginine - containing fragments in its degradation products”, J. Chromatogr. A, 1996, 736, 91-96.
58. H. Cui,
L.E. Reusaet and A. Bult*,
“Selective determination of peptides containing specific amino acid
residues in high performance liquid chromatography and capillary
electrophoresis”, J. Chromatogr. A, 1995,
704, 27-36.
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